Despite five decades of intensive research, predicting which patients will die by suicide remains no more accurate than flipping a coin. This stark reality drives mental health experts to focus on preventing access to lethal means rather than relying on risk assessments that consistently fail. Paul Nestadt, medical director at the Johns Hopkins Center for Suicide Prevention, treats suicidal patients, co-authors research papers, and teaches graduate courses on suicide prevention. Yet he admits he cannot identify which patients will die by suicide within six months. Research demonstrates that suicide predictions have not improved over the past 50 years, showing only marginally better accuracy than random chance. This limitation pushes Nestadt and other clinicians toward interventions that do not require pinpointing at-risk individuals. Making it harder for people to carry out the act of killing themselves emerges as the most promising strategy, though it faces significant political and constitutional obstacles. More than 28,000 people killed themselves with firearms last year, representing over half of all suicide deaths in the United States, according to preliminary federal data. Gun Suicides Reach Unprecedented Levels Even as overall suicide rates have dipped recently, gun suicides have hit record highs for five consecutive years. The crisis extends beyond traditional high-risk groups. While middle-aged white men and veterans continue to show elevated suicide rates, recent increases appear among women and some Black and Latino men, reflecting broader shifts in firearm ownership patterns. Researchers attribute part of this surge to the pandemic-era wave of first-time gun buyers. The influx of new firearms into homes across diverse demographics underscores the urgent need for prevention efforts that can be applied widely, rather than targeting specific populations. This demographic expansion of gun ownership complicates traditional suicide prevention strategies that focus on identifying and treating at-risk individuals. “Instead of asking every doctor to figure out which patient will die by suicide and locking that patient up, it might be that we need to make sure there aren’t loaded guns available,” Nestadt said. KFF Health News is examining approaches to suicide prevention that expand beyond providing people at risk with medication and therapy in an ongoing series. Although those interventions are lifesaving measures, many clinicians, researchers, and people who have lost loved ones to suicide agree that more comprehensive strategies are needed. The challenge intensifies when prevention efforts involve firearms, as broad policy approaches quickly become constitutionally complicated and politically polarizing. Limiting Access to Lethal Means Shows Greatest Promise Research shows that limiting access to lethal means ranks as one of the most promising approaches to save lives. This strategy can involve erecting barriers on buildings and bridges to prevent people from jumping, as well as decreasing the number of pills someone can buy or be prescribed at once. Nestadt identifies means restriction as the intervention that will save the most lives. The approach may also prove the most difficult to achieve, particularly regarding firearms in the United States. Constitutional protections and cultural attitudes toward gun ownership create formidable barriers to policy implementation. Yet the evidence supporting means restriction continues to accumulate, showing that many suicide attempts are impulsive acts that can be prevented if the most lethal methods are not immediately available. Suicide prevention traditionally relies on identifying high-risk individuals through screening tools and clinical judgment. The persistent inability to predict suicide attempts with reasonable accuracy, combined with rising gun suicide rates, forces a strategic shift. Rather than perfecting prediction methods that have shown no improvement in half a century, experts increasingly advocate for population-level interventions that reduce opportunity regardless of individual risk assessment. Demographic Shifts Complicate Prevention Efforts The changing demographics of gun suicide victims demand broader prevention strategies. While veterans and middle-aged white men have historically shown elevated suicide rates, recent increases among women and minority populations signal that firearm access poses widening public health risks. These demographic shifts correlate with changing patterns of gun ownership across American society. The COVID-19 pandemic accelerated firearm purchases among populations that previously had lower rates of gun ownership. This expansion introduces suicide risk factors into households and communities where prevention messaging and safety measures may be less established. First-time gun buyers often lack training in secure storage practices that can prevent impulsive access during crisis moments. Mental health professionals face a difficult balance between respecting patient autonomy and implementing safety measures. Nestadt’s acknowledgment that he cannot predict which patients will die by suicide reflects the limitations of individual clinical assessment. The focus on means restriction represents a pragmatic response to these limitations, targeting the method rather than attempting to identify every at-risk person. Policy Challenges Block Proven Prevention Methods Despite strong research evidence supporting means restriction, implementation faces substantial obstacles. Gun rights advocacy groups view restrictions on firearm access as infringing on constitutional protections. This political polarization prevents adoption of policies that public health experts identify as most effective for reducing suicide deaths. The public health community struggles to frame suicide prevention in ways that bridge political divides. While other forms of means restriction, such as bridge barriers and pill packaging limits, generate less controversy, firearms remain a contentious issue. Johns Hopkins Center for Suicide Prevention researchers continue seeking approaches that save lives while respecting diverse perspectives on gun ownership. The persistence of over 28,000 annual gun suicide deaths despite declining overall suicide rates demonstrates the unique lethality and availability of firearms. Unlike many suicide methods, guns require minimal preparation and leave little opportunity for intervention or survival. This combination makes firearm access a critical factor in suicide mortality, even as other risk factors remain constant or improve. Post navigation Medical Bills Expose Gaps in Emergency Care Protections as Patients Face Tens of Thousands in Unexpected Charges FDA Advisory Panel Weighs First Multi-Cancer Blood Test as Industry Watches Closely